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Only in 13 cases (31.7%) was a major pathology found (such as idiopathic QT prolongation, obesity, hypertension, bicuspid aortic valve, dilatation of the ascending aorta, and tetralogy of Fallot)

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at 1-800-845-8210 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch Drug Interactions Hepatic enzyme-inducing drugs (e.g., phenytoin, carbamazepine, phenobarbital, primidone, rifampin) can increase valproate clearance, while enzyme inhibitors (e.g., felbamate) can decrease valproate clearance

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Moderate traumatic brain injury promotes proliferation of quiescent neural progenitors in the adult hippocampus